منابع مشابه
Danger Signals in Cardiovascular Disease
1 Department of Internal Medicine I, University Hospital Würzburg, Comprehensive Heart Failure Center, University of Würzburg, Oberdürrbacher Straße 6, 97080 Würzburg, Germany 2 Comprehensive Heart Failure Center, University of Würzburg, Germany 3 Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London W6 8LH, UK 4Laboratory of Experimental Cardiology, University Medic...
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An important issue at the design stage of the auditory danger signal for a safety system is the signal audibility under various conditions of background noise. The auditory danger signal should be clearly audible but it should not be too loud to avoid fright, startling effects, and nuisance complaints. Criteria for designing auditory danger signals are the subject of the ISO 7731 (International...
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One of the key hazardous events in railways is signals passed at danger (SPAD). SPAD events are relatively common, most with minor consequence. However, SPAD events with catastrophic consequences happen sufficiently often to be a concern within the rail industry. A SPAD event is a precursor to a train collision or derailment; hence there is a strong focus on measuring and reducing their frequen...
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Staphylococcal enterotoxin B (SEB) of Staphylococcus aureus, and related superantigenic toxins produced by myriad microbes, are potent stimulators of the immune system causing a variety of human diseases from transient food poisoning to lethal toxic shock. These protein toxins bind directly to specific Vβ regions of T-cell receptors (TCR) and major histocompatibility complex (MHC) class II on a...
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Viruses efficiently block the host antiviral response in order to replicate and spread before host intervention. The mechanism initiating antiviral immunity during stealth viral replication is unknown, but recent data demonstrate that defective viral genomes generated at peak virus replication are critical for this process in vivo. This article summarizes the supporting evidence and highlights ...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2007
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2240